Question #335
Which of the following transporters mediates the uptake of fructose?
Sodium-coupled active transport of glucose across the apical membranes of intestinal and renal epithelial cells is mediated by SGLT-1 and -2.
GLUT-1 is found on all mammalian cell membranes and is responsible for basal glucose uptake. GLUT-2 is found on intestinal, renal tubular and pancreatic beta cell membranes and is able to bind all monosaccharides. GLUT3 is found on neuronal membranes. GLUT4 is found in fat and striated muscle cell membranes: is is insulin-dependent. GLUT5 transports fructose.