Question #298

Anti-diuretic hormone (ADH) acts on the principal cells of the collecting duct to:

activate V1 receptors

stimulate the insertion of vasopressin-regulated urea transporters (VRUTs) into the luminal side of the tubular membrane

stimulate the insertion of aquaporin-3 (AQP3) transporters into the luminal side of the tubular membrane

indirectly stimulate the secretion of erythropoietin

stimulate the secretion of renin

ADH acts on V1 receptors in the vasculature and V2 receptors in the kidney.

Aquaporins 1 and 2 are found in the luminal membrane while aquaporins 3 and 4 are found in the basolateral membrane.

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